EHA and TIF explore how COVID-19 is affecting thalassemia and SCD patients. 24. States with religious and philosophical exemptions from school immunization requirements. Marion Cook. While the research is early and there is much left to be learned, people who have thalassemia (at least some types) may be more susceptible to contracting coronavirus and having a serious outcome. Orphanet J Rare Dis. Most states offer religious exemptions from school vaccine requirements, and some provide exemptions on philosophical grounds. Since hemoglobin levels already run low for many people with thalassemia, the combination of factors has raised some concerns. Should you get a COVID vaccine if you have beta thalassemia? An official website of the United States government. Eur J Haematol. Key points about beta thalassemia in children. The coronavirus disease 2019 (COVID-19) is an emerging infectious disease that has become a global public health concern after being first reported in China and has subsequently spread worldwide. (2022). Beta thalassemia major (Cooley's anemia). eCollection 2022 Aug. See this image and copyright information in PMC. A comprehensive review of studies published in Seminars in Vascular Surgery in September 2021 examined peer-reviewed journal articles published from March 2020 to January 2021. Accessibility When looking into thalassemia and COVID-19 risk, it's important to identify both the risk of potential exposure and susceptibility. Treatment may include regular blood transfusions. Some researchers hypothesize that thalassemia might be protective against COVID-19 as it is against malaria. When one of these two genes are missing, it can lead to beta thalassemia trait, or beta thalassemia minor. The results align with the results of other studies from countries around the world. Blood types can also serve as receptors for viruses and bacteria, and that could be another factor, explained Dr. Russo, there may be some other, completely different component of type O blood that works to prevent infection. Beta-thalassemia causes symptoms related to anemia, including weak or brittle bones, and leads to problems with how your bones develop. chenevex, France. We avoid using tertiary references. A 2022 study found that people with beta-thalassemia trait were also at increased risk of severe illness from COVID-19. This condition can cause abrupt changes in blood pressure or heart rate that may worsen a person's condition during a COVID-19 infection. Beta thalassemia may protect against COVID 19. The current evidence suggests that the benefits of COVID-19 vaccination outweigh the risk of side effects for most people with autoimmune disease, according to the Global Autoimmune Institute, which reviewed the available scientific literature. (2014). Hemoglobin normally is made of four chainstwo alpha chains and two beta chains. If you have minor or no symptoms, your provider may suspect thalassemia based on the results of a routine blood test. How Might Swollen Glands Be a Sign of COVID-19? You likely wont have any symptoms. Getting COVID-19 offers some natural protection or immunity from reinfection with the virus that causes COVID-19.It's estimated that getting COVID-19 and COVID-19 vaccination both result in a low risk of another infection with a similar variant for at least six months.. Diagnosis. All rights reserved. There has also been a shortage at other steps in the process, such as personnel available to perform collections, as well as process and deliver donated blood. Blood tests can also be used for . 2020;15(1):265.doi:10.1186/s13023-020-01543-0, Piga A, Perrotta S, Gamberini MR, et al. Orphanet J Rare Dis. While there are no specific guidelines at this time, some researchers believe that hemoglobin levels should be monitored closely in people with thalassemia if they develop COVID-19, even when symptoms are only mild.

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